Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671509 | 0.91 | NPC1 (0.46) | DHFRMLYCDMAPTSLC18A3HRH3 | |
| SCHEMBL29671594 | 0.82 | HRH3 (0.47) | MAPTHRH3DRD2CYP1A2CYP2C9 | |
| SCHEMBL29671571 | 0.78 | MAPT (0.52) | DHFRMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19152335 | 0.75 | HRH3 (0.48) | MAPTHRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7446491 | 0.74 | MBTD1 (0.55) | DHFRSLC18A3GRIN2BDRD2CYP1A2 | |
| SCHEMBL28699866 | 0.73 | DHFR (0.50) | DHFRMLYCDMAPTSLC18A3GRIN2B | |
| SCHEMBL23972249 | 0.72 | GRIN2D (0.52) | DHFRMLYCDMAPTHRH3GRIN2B | |
| SCHEMBL11922648 | 0.72 | HRH3 (0.40) | MAPTHRH3CYP1A2NPC1RAB9A | |
| SCHEMBL2393500 | 0.71 | DHFR (0.55) | DHFRMLYCDMAPTSLC18A3GRIN2B | |
| SCHEMBL22117672 | 0.71 | GRIN2B (0.51) | DHFRMLYCDMAPTSLC18A3GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | DHFR 4807/4885MLYCD 2756/4885MAPT 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.