Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23542718 | 0.80 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL8281296 | 0.76 | PARP1 (0.44) | SMN1; SMN2TDP1HPGDMEN1KMT2A | |
| SCHEMBL25058761 | 0.75 | L3MBTL1 (0.36) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL23306810 | 0.71 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL12826054 | 0.70 | TDP1 (0.39) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL9493698 | 0.69 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL19903965 | 0.69 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL9493702 | 0.69 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL20391067 | 0.67 | FURIN (0.42) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 | |
| SCHEMBL24247898 | 0.65 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TDP1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |