SCHEMBL2233576

SCHEMBL2233576

C[Si](O[SiH3])(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
TSHR P16473 2/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251487 0.80 ESR1 (0.33) ESR1ESR2
SCHEMBL211428 0.79 ESR1 (0.39) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL433139 0.78 ESR1 (0.42) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL7565872 0.77 ESR1 (0.38) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL704598 0.77 CA4 (0.42) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL704149 0.76 CA1 (0.41) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL21086726 0.75 NPC1 (0.37) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL332855 0.75 ESR1 (0.37) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL11034567 0.75 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL4781738 0.75 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3941978-A1 SILOXANE ADDITIVE MANUFACTURING COMPOSITION Spectroplast AG (CH) 2022-01-26 EP claimed
WO-2020187891-A1 SILOXANE ADDITIVE MANUFACTURING COMPOSITION SPECTROPLAST AG (CH) 2020-09-24 WO claimed
CN-119592182-A Polyether organic silicon composite material and method for preparing synthetic leather by using same 东莞市雄驰电子有限公司 2025-03-11 CN disclosed
CN-115334854-A Heat dissipation assembly, production method of heat dissipation assembly and electronic equipment 维沃移动通信有限公司 2022-11-11 CN disclosed
CN-112176443-A Preparation method of thermosensitive color-changing polyethylene fiber 湖南中泰特种装备有限责任公司 2021-01-05 CN disclosed
US-8946353-B2 Curable organopolysiloxane composition, optical semiconductor element sealant, and optical semiconductor device DOW CORNING TORAY CO. LTD. (JP) 2015-02-03 US disclosed
US-8440776-B2 Lens-forming silicone resin composition and silicone lens SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-14 US disclosed
US-8204424-B2 Cleaning blade for electrophotographic device and method for manufacturing the same BANDO CHEMICAL INDUSTRIES, LTD. (JP) 2012-06-19 US disclosed
US-8202933-B2 Silicone resin composition for encapsulating luminescent element and process for producing optical-semiconductor electronic part with the same through potting SANYU REC CO., LTD. (JP) 2012-06-19 US disclosed
US-20110254047-A1 Curable Organopolysiloxane Composition, Optical Semiconductor Element Sealant, And Optical Semiconductor Device DOW TORAY CO., LTD. (JP) 2011-10-20 US disclosed
EP-2352794-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, OPTICAL SEMICONDUCTOR ELEMENT SEALANT, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2011-08-10 EP disclosed
EP-0239961-B1 A SILICONE RUBBER COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 1992-10-21 EP disclosed
EP-0394918-A2 Curable phosphazene compositions and coated articles IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-10-31 EP disclosed
US-4755554-A Silicone rubber composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-05 US disclosed
EP-0239961-A2 A silicone rubber composition Shin-Etsu Chemical Co., Ltd. (JP) 1987-10-07 EP disclosed
EP-0075381-B1 SILOXANE CROSSLINKERS DOW CORNING CORPORATION (US) 1985-04-03 EP disclosed
US-4403082-A TRIS/DIMETHOXYSILOXY/SILYLALKYL CARBOXYLATE DOW CORNING CORPORATION (US) 1983-09-06 US disclosed
EP-0075381-A1 Siloxane crosslinkers DOW CORNING CORPORATION (US) 1983-03-30 EP disclosed
US-4360687-A AN ACYLOXYALKYL-TRIS (DIMETHYLSILOXY) SILANE HAVING SILICON-BONDED HYDROGEN DOW CORNING CORPORATION (US) 1982-11-23 US disclosed
US-3974122-A Heat-curable silicone resin compositions SHIN-ETSU CHEMICAL CO., LTD. (JA) 1976-08-10 US disclosed