SCHEMBL7565872

SCHEMBL7565872

C[Si]([SiH3])(O[SiH3])c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31
TSHR P16473 1/20 0.31
CA4 P22748 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2796775 0.78 ESR1 (0.44) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL211428 0.77 ESR1 (0.39) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL2233576 0.77 ESR1 (0.39) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL9296360 0.75 ESR1 (0.34) ESR1ESR2NR1H2NR1H3
SCHEMBL332855 0.73 ESR1 (0.37) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL11034567 0.73 ESR1 (0.37) ESR1ESR2NR1H2NR1H3
SCHEMBL2799324 0.73 ESR1 (0.44) ESR1ESR2NR1H2NR1H3TSHR
SCHEMBL11870662 0.71 ESR1 (0.35) ESR1ESR2MAPT
Potassium Ion SCHEMBL11866555 0.71 ESR1 (0.35) ESR1ESR2MAPT
SCHEMBL2284805 0.71 ESR1 (0.35) ESR1ESR2TSHRCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472114-B2 ELECTRIC CHARGE GENERATING MATERIAL, A BINDING RESIN, A SILICON OIL HAVING A SPECIFIED SURFACE TENSION, AND AN ORGANIC SOLVENT; FOR USE WITH COPIERS, A PRINTER OR A FACSIMILE SHARP KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-20020051921-A1 Coating fluid for electric charge generating layer, organic electrophotographic receptor, and method fo manufacturing the same SHARP KABUSHIKI KAISHA (JP) 2002-05-02 US disclosed