Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371575 | 0.80 | KMT2A (0.65) | SMN1; SMN2MEN1KMT2AKEAP1MAPK1 | |
| SCHEMBL22322535 | 0.80 | HNF4A (0.50) | ALDH1A1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30463435 | 0.78 | MEN1 (1.00) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL6677412 | 0.78 | MEN1 (1.00) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20578422 | 0.77 | MEN1 (0.96) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL30526771 | 0.76 | MAP4K1 (0.47) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL7445918 | 0.75 | MEN1 (0.86) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL8534623 | 0.74 | GABRA1 (0.65) | SMN1; SMN2MEN1KMT2AMAPK1ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28029146 | 0.74 | MEN1 (0.83) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL3760398 | 0.72 | MEN1 (0.74) | SMN1; SMN2MEN1KMT2AKEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161248-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |