Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20930629 | 0.95 | HRH4 (0.34) | ALDH1A1TSHRHRH4TP53TDP1 | |
| SCHEMBL13506873 | 0.89 | MAPT (0.37) | ALDH1A1HRH4KDM4EMAPTNPSR1 | |
| SCHEMBL13507393 | 0.88 | HRH4 (0.40) | ALDH1A1HRH4TP53TDP1KDM4E | |
| SCHEMBL13338507 | 0.81 | C5AR1 (0.38) | ALDH1A1TSHRTP53CHRNA7KDM4E | |
| SCHEMBL24237256 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53TDP1CHRNA7 | |
| SCHEMBL22336312 | 0.79 | CYP1A2 (0.37) | ALDH1A1HRH4TP53TDP1MAPT | |
| SCHEMBL10047612 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CHRNA7KDM4E | |
| SCHEMBL20149501 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53TDP1KDM4E | |
| SCHEMBL19958559 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53TDP1KDM4E | |
| SCHEMBL7765869 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| WO-2020162600-A1 | POLYCYCLIC AROMATIC COMPOUND | 学校法人関西学院 | 2020-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | ALDH1A1 2814/4885TSHR 1102/4885HRH4 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.