Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996452 | 0.88 | ALDH1A1 (0.39) | ALDH1A1TSHRRAPGEF4NPSR1MAPT | |
| SCHEMBL24237261 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPTCHRNA7MCOLN3 | |
| SCHEMBL26996634 | 0.86 | DHFR (0.38) | ALDH1A1TSHRNPSR1MAPTFFAR4 | |
| SCHEMBL19203365 | 0.85 | TSHR (0.43) | ALDH1A1TSHRMAPTCHRNA7MCOLN3 | |
| SCHEMBL24237257 | 0.83 | AR (0.41) | ALDH1A1TSHRRAPGEF4NPSR1MAPT | |
| SCHEMBL21913732 | 0.82 | RAPGEF4 (0.38) | ALDH1A1TSHRRAPGEF4NPSR1MAPT | |
| SCHEMBL10047612 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPTCHRNA7MCOLN3 | |
| SCHEMBL18634724 | 0.81 | ALDH1A1 (0.34) | ALDH1A1TSHRRAPGEF4NPSR1MAPT | |
| SCHEMBL13338508 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRRAPGEF4NPSR1MAPT | |
| SCHEMBL22336311 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRRAPGEF4NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20220037591-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | ALDH1A1 2814/4885TSHR 1102/4885RAPGEF4 4795/4885 |
| US-20220037591-A1 | Polycyclic aromatic compound | F11, C1R, RNF31 | ALDH1A1 2814/4885TSHR 1102/4885RAPGEF4 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.