Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21609724 | 1.00 | HDAC3 (0.41) | HDAC3HDAC1HDAC2NFE2L2RAB9A | |
| SCHEMBL22336947 | 0.88 | RAB9A (0.38) | HDAC3HDAC1HDAC2RAB9ANPC1 | |
| SCHEMBL21609723 | 0.88 | RAB9A (0.38) | HDAC3HDAC1HDAC2RAB9ANPC1 | |
| SCHEMBL21609715 | 0.82 | HPGD (0.52) | NFE2L2RAB9ANPC1KMT2ACRBN | |
| SCHEMBL21609714 | 0.82 | HPGD (0.52) | NFE2L2RAB9ANPC1KMT2ACRBN | |
| SCHEMBL22337189 | 0.80 | MAOA (0.43) | KMT2ACRBNMAPTTDP1SMN1; SMN2 | |
| SCHEMBL21609713 | 0.80 | MAOA (0.43) | KMT2ACRBNMAPTTDP1SMN1; SMN2 | |
| SCHEMBL3290861 | 0.78 | NFE2L2 (0.37) | NFE2L2RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL6478831 | 0.77 | KMT2A (0.48) | RAB9ANPC1KMT2AHPGDALDH1A1 | |
| SCHEMBL22558220 | 0.76 | ALDH1A1 (0.44) | HDAC3HDAC1HDAC2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255457-A1 | PROCESS FOR THE REMOVAL AND RETURN OF A CATALYST TO A LIQUID PHASE MEDIUM | PHOSPHONICS LTD (GB) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255457-A1 | PROCESS FOR THE REMOVAL AND RETURN OF A CATALYST TO A LIQUID PHASE MEDIUM | MSR1, NOC2L, GFRA2 | HDAC3 3490/4885HDAC1 3465/4885HDAC2 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.