SCHEMBL223379

SCHEMBL223379

Brc1cccc(SSc2cccc(Br)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 1/20 0.46
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MGLL Q99685 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
HSP90AA1 P07900 1/20 0.41
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
C1S P09871 1/20 0.38
PARP1 P09874 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
GRM5 P41594 1/20 0.38
DCUN1D1 Q96GG9 1/20 0.37
IDO1 P14902 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31412109 1.00 MAOA (0.48) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL19718024 0.91 MAOA (0.43) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL22051340 0.87 ALDH1A1 (0.64) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL29543964 0.83 MAOA (0.48) MAOAALDH1A1MAPK1DDB1CRBN
SCHEMBL31337906 0.83 MAOA (0.48) MAOAALDH1A1MAPK1DDB1CRBN
SCHEMBL3289392 0.83 MAOA (0.48) MAOAALDH1A1MAPK1DDB1CRBN
SCHEMBL1647481 0.83 MAOA (0.39) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL10595966 0.81 MAOA (0.47) MAOAALDH1A1MAPK1DDB1CRBN
SCHEMBL1646503 0.80 MAOA (0.47) MAOAALDH1A1MAPK1MAPTDDB1
SCHEMBL513927 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 983 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117802511-A Preparation method of thiosulfate compound 西华大学 2024-04-02 CN claimed
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-20250018250-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-01-16 US disclosed
US-20240299812-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-09-12 US disclosed
US-20240269520-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2024-08-15 US disclosed
CN-117802511-A Preparation method of thiosulfate compound 西华大学 2024-04-02 CN disclosed
US-11712605-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-08-01 US disclosed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US disclosed
US-4983720-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-01-08 US disclosed
EP-0402481-A1 PRODUCTION OF POLYARYLENE THIOETHER RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1990-12-19 EP disclosed
US-4931542-A Process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL COMPANY, LIMITED (JP) 1990-06-05 US disclosed
EP-0281036-A2 A process for preparing a polyarylene thioether IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-07 EP disclosed
US-4727178-A Process for preparing phosphorodichloridothiolate STAUFFER CHEMICAL CO. (US) 1988-02-23 US disclosed
US-4056581-A Process for the preparation of phosphorodichloridothiolates ROHM AND HAAS COMPANY (US) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 MAOA 4880/4885ALDH1A1 2276/4885MAPK1 3401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.