SCHEMBL1647481

SCHEMBL1647481

Clc1c(Cl)c(Cl)c(SSc2cccc(Br)c2)c(Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
FBP1 P09467 1/20 0.33
HSP90AA1 P07900 1/20 0.32
GRM5 P41594 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MGLL Q99685 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31412109 0.83 MAOA (0.48) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL223379 0.83 MAOA (0.48) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL1646146 0.80 FBP1 (0.49) ALDH1A1HPGDHSD17B10CYP1A2CYP2C9
SCHEMBL1646794 0.79
SCHEMBL19718024 0.75 MAOA (0.43) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL1648429 0.75 FBP1 (0.40) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL3798472 0.74 HPGD (0.60) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL1648011 0.74
SCHEMBL22051340 0.72 ALDH1A1 (0.64) MAOAALDH1A1MAPK1HPGDHSD17B10
SCHEMBL8086010 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed