SCHEMBL1646503

SCHEMBL1646503

CCSSc1cccc(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.47
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAOB P27338 2/20 0.36
GAA P10253 1/20 0.36
KDM1A O60341 1/20 0.36
RCOR1 Q9UKL0 1/20 0.36
TAAR1 Q96RJ0 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
C1S P09871 1/20 0.34
PARP1 P09874 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
TYMS P04818 1/20 0.34
DDB1 Q16531 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223379 0.80 MAOA (0.48) MAOAALDH1A1MAPK1MAPTTAAR1
SCHEMBL31412109 0.80 MAOA (0.48) MAOAALDH1A1MAPK1MAPTTAAR1
SCHEMBL31299577 0.79 MAOA (0.59) MAOAALDH1A1MAPK1MAPTNPSR1
SCHEMBL100217 0.79 MAOA (0.59) MAOAALDH1A1MAPK1MAPTNPSR1
SCHEMBL1645351 0.79 FBP1 (0.32)
SCHEMBL3888593 0.78 ACHE (0.44) MAOAALDH1A1MAPK1MAPTMAOB
SCHEMBL1647142 0.78 FBP1 (0.45) MAOAALDH1A1MAPTMAOBGAA
SCHEMBL776041 0.76 ACHE (0.40) MAOAMAOBKDM1ARCOR1TAAR1
SCHEMBL1646234 0.74 MAOA (0.41) MAOAALDH1A1MAPK1MAPTMAOB
SCHEMBL22051340 0.73 ALDH1A1 (0.64) MAOAALDH1A1MAPK1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed