Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | CBS | P35520 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20755257 | 0.84 | KDM4E (0.34) | THPO | |
| SCHEMBL20744883 | 0.83 | TSHR (0.33) | GPR55TSHRCTHCBSTHPO | |
| SCHEMBL20744886 | 0.83 | TSHR (0.33) | GPR55TSHRCTHCBSTHPO | |
| SCHEMBL20755618 | 0.82 | MGAM (0.33) | TSHR | |
| SCHEMBL20745216 | 0.80 | GPR55 (0.36) | GPR55TSHRCTHCBSTHPO | |
| SCHEMBL20745215 | 0.80 | GPR55 (0.36) | GPR55TSHRCTHCBSTHPO | |
| SCHEMBL22337957 | 0.80 | GPR55 (0.35) | GPR55TSHRCTHCBSTHPO | |
| SCHEMBL22337953 | 0.79 | GPR55 (0.31) | GPR55TSHRCTHCBSTHPO | |
| SCHEMBL20755256 | 0.74 | — | — | |
| SCHEMBL20744888 | 0.74 | HPGD (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | THE SCRIPPS RESEARCH INSTITUTE | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255363-A1 | Directed Beta-C(sp3)–H Iodination and Arylation of Ketones | BCAT1, AOC3, SPIN3 | GPR55 4340/4885TSHR 797/4885CTH 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.