Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606466 | 0.90 | TSHR (0.55) | L3MBTL1ALDH1A1MAPK1TSHRNMT1 | |
| Hydrochloric Acid SCHEMBL3494457 | 0.88 | TSHR (0.57) | ALDH1A1TSHRNMT1SMN1; SMN2NPC1 | |
| SCHEMBL3706643 | 0.87 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MAPK1TSHRLMNA | |
| Alcohol SCHEMBL27541427 | 0.84 | TSHR (0.53) | ALDH1A1TSHRPKMNMT1SMN1; SMN2 | |
| SCHEMBL28687641 | 0.84 | TSHR (0.53) | ALDH1A1TSHRNMT1SMN1; SMN2NPC1 | |
| SCHEMBL3922320 | 0.82 | NMT1 (0.50) | L3MBTL1ALDH1A1MAPK1GLATSHR | |
| SCHEMBL6535407 | 0.82 | TSHR (0.47) | ALDH1A1TSHRNMT1SMN1; SMN2NPC1 | |
| SCHEMBL27953261 | 0.82 | TSHR (0.44) | L3MBTL1ALDH1A1TSHRLMNAPKM | |
| SCHEMBL5222777 | 0.81 | TSHR (0.52) | ALDH1A1GLATSHRPKMSMN1; SMN2 | |
| SCHEMBL15626865 | 0.81 | TSHR (0.52) | ALDH1A1GLATSHRPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200253900-A1 | Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof | 3I, LP | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200253900-A1 | Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof | ACHE, COMT, CES2 | L3MBTL1 3547/4885ALDH1A1 795/4885MAPK1 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.