Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22302993 | 1.00 | NLRP3 (0.59) | NLRP3HDAC1HDAC6CTSGCMA1 | |
| SCHEMBL22285670 | 0.86 | ITGB3 (0.52) | NLRP3ACACB | |
| SCHEMBL22285669 | 0.86 | ITGB3 (0.52) | NLRP3ACACB | |
| SCHEMBL6139160 | 0.86 | NLRP3 (0.58) | NLRP3HDAC1HDAC6CTSGCMA1 | |
| SCHEMBL11925979 | 0.84 | GAA (0.60) | NLRP3CTSGCMA1 | |
| SCHEMBL25446628 | 0.83 | MDM4 (0.64) | NLRP3HDAC1HDAC6MDM4MDM2 | |
| SCHEMBL11940462 | 0.83 | MDM4 (0.64) | NLRP3HDAC1HDAC6MDM4MDM2 | |
| SCHEMBL22338883 | 0.82 | LNPEP (0.53) | HDAC1HDAC6MDM4MDM2POLB | |
| SCHEMBL22303600 | 0.82 | LNPEP (0.53) | HDAC1HDAC6MDM4MDM2POLB | |
| SCHEMBL22303780 | 0.82 | TAS1R3 (0.54) | HDAC1HDAC6MDM4MDM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163554-A1 | IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2020-08-13 | — | — | WO | disclosed |