SCHEMBL223388

SCHEMBL223388

CCOC(=O)C(C(=O)OCC)=C(C)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
LMNA P02545 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GLO1 Q04760 1/20 0.48
MAPT P10636 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALOX15 P16050 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
SOAT1 P35610 1/20 0.42
TSHR P16473 1/20 0.41
EGLN1 Q9GZT9 1/20 0.40
TRPA1 O75762 1/20 0.39
CYP2D6 P10635 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FAAH O00519 2/20 0.37
CYP1A2 P05177 1/20 0.37
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2357523 0.90 GLO1 (0.50) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL3678281 0.90 GLO1 (0.50) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL3678277 0.90 GLO1 (0.50) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL9794499 0.88 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL9794502 0.88 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL30250058 0.86 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL30250322 0.86 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL10928182 0.86 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL27613337 0.85 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL11771651 0.85 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GLO1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156698-B Preparation method and application of 2-phenyl-1, 6-dihydropyrimidine-5-formic acid derivative 沈阳海诺威医药科技有限公司 2020-10-13 CN claimed
US-20260132127-A1 NOVEL SPIRO COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2026-05-14 US disclosed
CN-118176179-A Novel spiro compounds 田边三菱制药株式会社 2024-06-11 CN disclosed
EP-4289480-A2 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS F. Hoffmann-La Roche AG (CH) 2023-12-13 EP disclosed
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
EP-3968983-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS HOFFMANN LA ROCHE (CH) 2023-09-13 EP disclosed
EP-4214214-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN Pharmaceutica NV (BE) 2023-07-26 EP disclosed
CN-116171280-A Casein kinase 1 delta modulators 詹森药业有限公司 2023-05-26 CN disclosed
WO-2023074847-A1 NOVEL SPIRO COMPOUND 田辺三菱製薬株式会社 2023-05-04 WO disclosed
CN-115215923-A Macrocyclic broad spectrum antibiotics 豪夫迈·罗氏有限公司 2022-10-21 CN disclosed
WO-2004056823-A1 PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-07-08 WO disclosed
WO-2004024728-A2 PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS GLAXO GROUP LIMITED (GB) 2004-03-25 WO disclosed
EP-0565096-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1999-07-07 EP disclosed
US-5691125-A CYAN DYE-FORMING COUPLER, STORAGE STABLE FUJI PHOTO FILM CO., LTD. (JP) 1997-11-25 US disclosed
US-5631122-A LIGHT SENSITIVE ELEMENTS FOR COLOR STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-05-20 US disclosed
US-5578436-A EXCELLENT SENSITIVITY/GRAININESS RATIO AND COLOR REPRODUCTION FUJI PHOTO FILM CO., LTD. (JP) 1996-11-26 US disclosed
US-5344933-A Pyrrole ring-or condensed pyrrole ring-containing azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 1994-09-06 US disclosed
EP-0565096-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-10-13 EP disclosed
EP-0563985-A1 Silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1993-10-06 EP disclosed
US-4522944-A ANTIINFLAMMATORY AGENTS AND PAIN KILLERS FARMITALIA CARLO ERBA S.P.A., MILAN ITALY A CORP OF ITALY (IT) 1985-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339970-A1 CASEIN KINASE 1 DELTA MODULATORS CSNK1D, CSNK1A1, CSNK1G1 ALDH1A1 1482/4885LMNA 3260/4885HSD17B10 1590/4885
US-20260132127-A1 NOVEL SPIRO COMPOUND TRHR, NR3C2, THRB ALDH1A1 1063/4885LMNA 2025/4885HSD17B10 388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.