SCHEMBL22339704

SCHEMBL22339704

CC[C@H](CCCB(O)O)C(C)(N)CC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 10/20 0.39
ARG2 P78540 10/20 0.39
ANPEP P15144 1/20 0.37
GGT1 P19440 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23468408 0.78 CA2 (0.39)
SCHEMBL23586079 0.76 ARG2 (0.51) ARG1ARG2GGT1
SCHEMBL23586104 0.76 ARG2 (0.51) ARG1ARG2GGT1
SCHEMBL5013324 0.72 TSHR (0.33)
SCHEMBL20683381 0.63 ARG1 (0.58) ARG1ARG2GGT1
SCHEMBL868015 0.62 ALDH1A1 (0.42)
SCHEMBL20243182 0.61 ARG2 (0.50) ARG1ARG2ANPEPGGT1
SCHEMBL10206688 0.61 ARG2 (0.50) ARG1ARG2ANPEPGGT1
SCHEMBL10732337 0.61
SCHEMBL20683341 0.60 ARG1 (0.61) ARG1ARG2ANPEPGGT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020160707-A1 ALKYLBORONIC ACIDS AS ARGINASE INHIBITORS GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) 2020-08-13 WO disclosed