Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22324848 | 0.80 | QDPR (0.58) | QDPRSIGMAR1CCNT1CDK9MEN1 | |
| SCHEMBL22340506 | 0.77 | HTR1A (0.49) | SIGMAR1MAPT | |
| SCHEMBL13801238 | 0.76 | MEN1 (0.47) | MEN1POLBKMT2AMAPTKDM4E | |
| SCHEMBL22324790 | 0.75 | GRM1 (0.54) | QDPRSUV39H2 | |
| SCHEMBL22340527 | 0.74 | SLC6A4 (0.42) | CCNT1CDK9PDE4D | |
| SCHEMBL13801237 | 0.73 | TNKS (0.51) | CCNT1CDK9PDE4DPTGS2MAPT | |
| SCHEMBL20500724 | 0.72 | PTGS2 (0.45) | CCNT1CDK9PDE4DPTGS2PTGS1 | |
| SCHEMBL14141231 | 0.72 | L3MBTL1 (0.48) | MEN1KMT2AALDH1A1ALOX15RAB9A | |
| SCHEMBL22340528 | 0.69 | MEN1 (0.46) | QDPRPDE4DMEN1POLBKMT2A | |
| SCHEMBL12326172 | 0.69 | PTGS2 (0.53) | PTGS2PTGS1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163689-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-13 | — | — | WO | disclosed |