SCHEMBL22340698

SCHEMBL22340698

CCCCCCCCCN(Cc1cccc(OC)c1)c1ccc(OC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.49
ACHE P22303 2/20 0.46
BCHE P06276 1/20 0.46
QPCT Q16769 1/20 0.46
EPHX2 P34913 2/20 0.46
USP2 O75604 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
NR1H2 P55055 2/20 0.45
NR1H3 Q13133 2/20 0.45
APAF1 O14727 1/20 0.45
NR1I2 O75469 1/20 0.45
HSP90AA1 P07900 1/20 0.45
IDE P14735 1/20 0.45
UBE2N P61088 1/20 0.45
CALM1 P0DP23 1/20 0.44
CAMKK2 Q96RR4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20871434 1.00 CNR2 (0.49) CNR2ACHEBCHEQPCTEPHX2
SCHEMBL29334921 1.00 CNR2 (0.49) CNR2ACHEBCHEQPCTEPHX2
SCHEMBL20871827 1.00 CNR2 (0.49) CNR2ACHEBCHEQPCTEPHX2
SCHEMBL20870816 1.00 CNR2 (0.49) CNR2ACHEBCHEQPCTEPHX2
SCHEMBL20871152 0.99 CNR2 (0.47) CNR2ACHEBCHEQPCTEPHX2
SCHEMBL22340747 0.95 NR1H2 (0.49) CNR2ACHEBCHEQPCTEPHX2
SCHEMBL20871185 0.89 QPCT (0.50) CNR2BCHEQPCTTSHRCALM1
SCHEMBL20870818 0.89 CNR2 (0.47) CNR2USP2LMNACYP1A2CYP2D6
SCHEMBL29334940 0.89 CNR2 (0.47) CNR2USP2LMNACYP1A2CYP2D6
SCHEMBL29335717 0.89 CNR2 (0.47) CNR2USP2LMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707132-B1 NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES UNIV PARIS SACLAY (FR) 2024-07-17 EP disclosed
US-11034646-B2 Method for the synthesis of unsymmetrical tertiary amines Universite Paris-Saclay (FR) 2021-06-15 US disclosed
US-20200255369-A1 NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES Universite Paris-Saclay (FR) 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200255369-A1 NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES ADH1C, ADH1A, ADH5 CNR2 1633/4885ACHE 1378/4885BCHE 307/4885
US-11034646-B2 Method for the synthesis of unsymmetrical tertiary amines ADH1C, PNMT, ADH1A CNR2 2182/4885ACHE 1421/4885BCHE 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.