SCHEMBL22342117

SCHEMBL22342117

CCCCCCCCCCC(CCCCCCCC)Cc1c(C(N)=O)c(CC(CCCCCCCC)CCCCCCCCCC)c(C(N)=O)c(CC(CCCCCCCC)CCCCCCCCCC)c1C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
LAP3 P28838 2/20 0.42
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41
GPR84 Q9NQS5 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
SPHK1 Q9NYA1 1/20 0.40
FFAR1 O14842 1/20 0.40
MAPT P10636 1/20 0.39
TP53 P04637 1/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
S1PR2 O95136 5/20 0.39
S1PR1 P21453 5/20 0.39
S1PR3 Q99500 5/20 0.39
S1PR4 O95977 4/20 0.39
SLC1A2 P43004 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342134 0.86 CA2 (0.48) LMNACA1CA2TP53
Formamide SCHEMBL22658137 0.79 PRSS1 (0.33) LMNAMAPT
SCHEMBL23041978 0.76 GPR84 (0.38) LMNAGRIK1GRIK2GPR84CA1
SCHEMBL17688581 0.75 SCD (0.41) LMNAMAPTTP53
SCHEMBL28737637 0.75 SCD (0.41) LMNAMAPTTP53
SCHEMBL27708958 0.75 SCD (0.41) LMNAMAPTTP53
SCHEMBL20746315 0.71 LMNA (0.52) LMNALAP3GRIK1GRIK2GPR84
SCHEMBL22404357 0.71 LMNA (0.52) LMNALAP3GRIK1GRIK2GPR84
SCHEMBL12231548 0.71 LMNA (0.52) LMNALAP3GRIK1GRIK2GPR84
SCHEMBL21207649 0.71 SOAT1 (0.53) LMNAGPR84FFAR1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024613-B2 Composition containing a polymer and an additive École Polytechnique Fédérale De Lausanne (EPFL)—Technology Transfer Office (TTO) (CH) 2024-07-02 US disclosed
WO-2020229857-A1 COMPOSITION AND METHOD FOR THE PREPARATION OF SHEETS, FILMS, FIBERS, AND MOLDED PARTS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2020-11-19 WO disclosed
WO-2020229594-A1 COMPOSITION AND METHOD FOR THE PREPARATION OF SHEETS, FILMS, FIBERS, AND MOLDED PARTS ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) 2020-11-19 WO disclosed
US-20200299484-A1 COMPOSITION CONTAINING A POLYMER AND AN ADDITIVE ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) - TECHNOLOGY TRANSFER OFFICE (TTO) (CH) 2020-09-24 US disclosed
EP-3694921-A1 COMPOSITION CONTAINING A POLYMER AND AN ADDITIVE Ecole Polytechnique Fédérale de Lausanne (EPFL) EPFL-TTO (CH) 2020-08-19 EP disclosed