SCHEMBL22342134

SCHEMBL22342134

CCCCC(CC)Cc1c(C(N)=O)c(CC(CC)CCCC)c(C(N)=O)c(CC(CC)CCCC)c1C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.48
CA1 P00915 2/20 0.48
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 6/20 0.41
CYP3A4 P08684 4/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 2/20 0.38
GLA P06280 1/20 0.38
MAPK1 P28482 2/20 0.37
LMNA P02545 3/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22342117 0.86 LMNA (0.44) CA2CA1LMNATP53
SCHEMBL7878129 0.84 CA2 (0.46) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL8959367 0.84 CA2 (0.46) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL29523183 0.81 TSHR (0.44) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL108345 0.81 TSHR (0.44) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL6684611 0.79 ALDH1A1 (0.51) CA2CA1ALDH1A1TDP1TSHR
Acetone SCHEMBL10535239 0.78 TSHR (0.41) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL22442276 0.78 TSHR (0.45) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL14989251 0.77 CA2 (0.44) CA2CA1ALDH1A1TDP1TSHR
SCHEMBL20920808 0.76 CA2 (0.41) CA2CA1ALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024613-B2 Composition containing a polymer and an additive École Polytechnique Fédérale De Lausanne (EPFL)—Technology Transfer Office (TTO) (CH) 2024-07-02 US disclosed
CN-114096602-B Composition and method for preparing sheets, films, fibers and shaped parts 洛桑联邦理工学院 (EPFL) 2024-02-13 CN disclosed
WO-2020229857-A1 COMPOSITION AND METHOD FOR THE PREPARATION OF SHEETS, FILMS, FIBERS, AND MOLDED PARTS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2020-11-19 WO disclosed
WO-2020229594-A1 COMPOSITION AND METHOD FOR THE PREPARATION OF SHEETS, FILMS, FIBERS, AND MOLDED PARTS ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) (CH) 2020-11-19 WO disclosed
US-20200299484-A1 COMPOSITION CONTAINING A POLYMER AND AN ADDITIVE ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) - TECHNOLOGY TRANSFER OFFICE (TTO) (CH) 2020-09-24 US disclosed
EP-3694921-A1 COMPOSITION CONTAINING A POLYMER AND AN ADDITIVE Ecole Polytechnique Fédérale de Lausanne (EPFL) EPFL-TTO (CH) 2020-08-19 EP disclosed
CN-107551962-B High-thermal-stability two-component organogel and preparation method thereof 中北大学 2020-06-02 CN disclosed