Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANXA2 | P07355 | 5/20 | 0.45 |
| ▸ | S100A10 | P60903 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234316 | 0.67 | ANXA2 (0.53) | ANXA2S100A10ALDH1A1POLBSMN1; SMN2 | |
| P-Cymene SCHEMBL11145451 | 0.63 | ACHE (0.44) | ANXA2S100A10SMN1; SMN2RAB9ASCN5A | |
| SCHEMBL26490140 | 0.62 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2NPSR1SCN5ASCN2A | |
| Terephthalic Acid SCHEMBL15994297 | 0.61 | ALDH1A1 (0.71) | ALDH1A1POLBSMN1; SMN2MAPTSCN5A | |
| P-Cymene SCHEMBL10388722 | 0.60 | ACHE (0.42) | ANXA2S100A10ALDH1A1SMN1; SMN2NPC1 | |
| P-Cymene SCHEMBL2404247 | 0.60 | CYP2C9 (0.52) | ALDH1A1POLBSMN1; SMN2MAPTRAB9A | |
| P-Cymene SCHEMBL29129736 | 0.59 | ACHE (0.47) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| P-Cymene SCHEMBL27525277 | 0.59 | CYP2C9 (0.50) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| P-Cymene SCHEMBL27355344 | 0.58 | ACHE (0.47) | SCN5ASCN2AUSP5LMNA | |
| P-Cymene SCHEMBL1073347 | 0.58 | ACHE (0.47) | SCN5ASCN2AUSP5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |