Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNMT | Q14749 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22343533 | 0.92 | GNMT (0.57) | GNMTADORA1TRPM2NT5EMETTL3 | |
| SCHEMBL22323629 | 0.92 | GNMT (0.56) | GNMTADORA1TRPM2NT5EDNPH1 | |
| SCHEMBL29702996 | 0.90 | ADORA1 (0.54) | GNMTADORA1TRPM2METTL3DNPH1 | |
| SCHEMBL22343675 | 0.90 | ADH1A (0.53) | GNMTADORA1TRPM2METTL3DNPH1 | |
| SCHEMBL29702967 | 0.88 | ADORA1 (0.52) | GNMTADORA1TRPM2METTL3 | |
| SCHEMBL22343548 | 0.88 | ADORA1 (0.52) | GNMTADORA1TRPM2METTL3 | |
| SCHEMBL22343764 | 0.88 | ADORA1 (0.54) | GNMTADORA1TRPM2NT5E | |
| SCHEMBL1434032 | 0.84 | ADORA1 (0.72) | ADORA1TRPM2METTL3DNPH1PRKAB2 | |
| SCHEMBL6905464 | 0.84 | ADORA1 (0.72) | ADORA1TRPM2METTL3DNPH1PRKAB2 | |
| SCHEMBL7165632 | 0.83 | ADORA1 (0.63) | ADORA1TRPM2NT5EMETTL3DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |