SCHEMBL2234441

SCHEMBL2234441

CCOC(=O)NNc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 9/20 1.00
SMN1; SMN2 Q16637 3/20 0.57
ALOX5 P09917 2/20 0.56
TDP1 Q9NUW8 4/20 0.55
LMNA P02545 3/20 0.55
MAPT P10636 2/20 0.55
MAPK1 P28482 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
NPC1 O15118 1/20 0.53
HPGD P15428 1/20 0.53
CRHBP P24387 1/20 0.53
RAB9A P51151 1/20 0.53
CRHR2 Q13324 1/20 0.53
HTT P42858 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
HIF1A Q16665 1/20 0.51
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28240039 0.98 GAA (0.96) GAASMN1; SMN2ALOX5TDP1LMNA
SCHEMBL1625209 0.83 GAA (0.71) GAASMN1; SMN2ALOX5TDP1LMNA
SCHEMBL14543254 0.82 GAA (0.77) GAASMN1; SMN2ALOX5TDP1MAPT
SCHEMBL679354 0.82 GAA (0.71) GAASMN1; SMN2TDP1LMNAMAPT
SCHEMBL9771276 0.82 GAA (0.70) GAASMN1; SMN2TDP1LMNAMAPT
SCHEMBL4908338 0.81 GAA (0.69) GAASMN1; SMN2TDP1LMNAMAPT
Ethyl Phenylcarbamate SCHEMBL264865 0.81 RAB9A (0.75) GAASMN1; SMN2LMNAMAPTMAPK1
Ethyl Phenylcarbamate SCHEMBL11593824 0.81 RAB9A (0.75) GAASMN1; SMN2LMNAMAPTMAPK1
SCHEMBL2236676 0.81 GAA (0.68) GAASMN1; SMN2TDP1NPC1HPGD
SCHEMBL10419324 0.81 GAA (0.68) GAASMN1; SMN2LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000030-B1 DIURETHANES CONTAINING SULPHUR, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1980-12-10 EP claimed
EP-0000030-A1 Diurethanes containing sulphur, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1978-12-20 EP claimed
CN-105001252-B Azocarbonyl-functionalized silanes 赢创德固赛有限公司 2019-12-24 CN disclosed
US-9981995-B2 Azocarbonyl-functionalized silanes EVONIK DEGUSSA GMBH (DE) 2018-05-29 US disclosed
EP-2937351-B1 AZOCARBONYL-FUNCTIONALIZED SILANES EVONIK DEGUSSA GMBH (DE) 2017-11-15 EP disclosed
CN-105642184-A Graphene dispersant and applications thereof 中国科学院宁波材料技术与工程研究所 2016-06-08 CN disclosed
EP-2937351-A1 Azocarbonyl-functionalized silanes Evonik Degussa GmbH (DE) 2015-10-28 EP disclosed
CN-105001252-A Azocarbonyl-functionalized silanes EVONIK INDUSTRIES AG 2015-10-28 CN disclosed
US-20150299228-A1 AZOCARBONYL-FUNCTIONALIZED SILANES EVONIK INDUSTRIES AG (DE) 2015-10-22 US disclosed
CN-102186811-B Process for producing bisoxazolinone compound and intermediate thereof SUMITOMO CO LTD 2013-07-24 CN disclosed
US-8299264-B2 Method for producing oxadiazolinone compound and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
CN-1092425-A Indole derivatives, its manufacture method and medicinal use thereof TORAY INDUSTRIES (JP) 1994-09-21 CN disclosed
EP-0553594-A1 Polymeric thermoplastic materials, comprising 1,2,4-triazolidine-3,5-dione derivatives as stabilisers CIBA-GEIGY AG (CH) 1993-08-04 EP disclosed
US-5196465-A Heat resistance CIBA-GEIGY CORPORATION (US) 1993-03-23 US disclosed
EP-0254294-B1 METHOD OF PROCESSING A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL AND A COLOR DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1992-12-23 EP disclosed
US-5086052-A Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis ABBOTT LABORATORIES (US) 1992-02-04 US disclosed
US-5064751-A Stability, antifogging FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
US-4970210-A ENZYME INHIBITORS ABBOTT LABORATORIES (US) 1990-11-13 US disclosed
EP-0299449-A2 Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1989-01-18 EP disclosed
US-4337263-A 1-Aryl-4-γ-arylsulphonyl-3-aminopropoxy-1H-pyrazoles and their use as hypolipemiant and hypocholesterolemiant agents LABORATOIRE ROGER BELLON (FR) 1982-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299228-A1 AZOCARBONYL-FUNCTIONALIZED SILANES RAD1, TAS1R1, TAS1R3 GAA 4131/4885SMN1; SMN2 3084/4885ALOX5 2314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.