Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429616 | 0.89 | GAA (0.59) | GAAP2RX7ALDH1A1MGLLPOLB | |
| SCHEMBL2295789 | 0.86 | CA12 (0.66) | GAAP2RX7ALDH1A1MGLLCA12 | |
| SCHEMBL38652348 | 0.85 | MGLL (0.57) | GAAP2RX7ALDH1A1MGLLCA12 | |
| SCHEMBL27706331 | 0.85 | NAMPT (0.60) | GAAP2RX7ALDH1A1MGLLPOLB | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.83 | POLB (0.78) | ALDH1A1MGLLPOLBSMN1; SMN2LMNA | |
| SCHEMBL27642853 | 0.82 | P2RX7 (0.50) | GAAP2RX7ALDH1A1MGLLCA12 | |
| SCHEMBL10619206 | 0.82 | USP2 (0.58) | GAAMGLLCA1CA2POLB | |
| SCHEMBL9673742 | 0.81 | ALDH1A1 (0.63) | P2RX7ALDH1A1MGLLCA12CA1 | |
| SCHEMBL2234441 | 0.81 | GAA (1.00) | GAAALDH1A1POLBSMN1; SMN2LMNA | |
| SCHEMBL11651843 | 0.81 | CA12 (0.60) | P2RX7ALDH1A1MGLLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096885-A1 | Quinoline Derivatives as Neurokinin Receptor Antagonists | MERCK SHARP & DOHME LTD. (GB) | 2008-04-24 | — | — | US | disclosed |
| EP-1536838-B1 | Hyposensibilisation by hydroxyalkyl starch allergen conjugates | FRESENIUS KABI DE GMBH (DE) | 2007-01-31 | — | — | EP | disclosed |
| US-20060121062-A1 | Conjugated hydroxyalkyl starch allergen compounds | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2006-06-08 | — | — | US | disclosed |
| EP-1536838-A1 | CONJUGATED HYDROXYALKYL STARCH ALLERGEN COMPOUNDS | Fresenius Kabi Deutschland GmbH (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004030701-A1 | CONJUGATED HYDROXYALKYL STARCH ALLERGEN COMPOUNDS | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096885-A1 | Quinoline Derivatives as Neurokinin Receptor Antagonists | TACR3, TACR2, TAC3 | GAA 1423/4885P2RX7 169/4885ALDH1A1 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.