SCHEMBL22345166

SCHEMBL22345166

CCCN(CCC)C(=O)CCC(=O)c1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.60
POLB P06746 1/20 0.59
APEX1 P27695 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
ATM Q13315 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HTT P42858 2/20 0.49
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 1/20 0.46
PAX8 Q06710 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PTPN1 P18031 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108987 0.91 HTR7 (0.66) HTR7POLBAPEX1TDP1NPC1
SCHEMBL1258171 0.87 HTR7 (0.59) HTR7NPC1RAB9AATMSMN1; SMN2
SCHEMBL25405722 0.84 KMT2A (0.49) NPC1RAB9ASMN1; SMN2KMT2ALMNA
SCHEMBL21191659 0.84 HDAC1 (0.47) POLBNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL3966037 0.80 NPC1 (0.60) HTR7POLBNPC1RAB9ASMN1; SMN2
SCHEMBL2490498 0.79 HTR7 (0.78) HTR7NPC1RAB9ASMN1; SMN2HTT
SCHEMBL26584242 0.78 NPC1 (0.82) HTR7NPC1RAB9ASMN1; SMN2HTT
SCHEMBL15221192 0.78 MLYCD (0.67) HTR7POLBAPEX1TDP1RAB9A
Hydrochloric Acid SCHEMBL10578417 0.77 HTR7 (0.75) HTR7NPC1RAB9ASMN1; SMN2HTT
SCHEMBL28988600 0.76 HTR7 (0.68) HTR7NPC1RAB9ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061083-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATGON (KR) 2026-03-05 US disclosed
US-12491271-B2 Positron emission tomography radiotracer for diseases associated with translocator protein overexpression, translocator protein-targeting ligand for fluorescence imaging-guided surgery and photodynamic therapy, and production methods therefor SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-12-09 US disclosed
US-20240156997-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-05-16 US disclosed
EP-3741392-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING DIAGNOSIS AND PHOTODYNAMIC THERAPY, AND PREPARATION METHOD THEREFOR Seoul National University R & DB Foundation (KR) 2020-11-25 EP disclosed
US-20200345870-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2020-11-05 US disclosed
WO-2019143016-A9 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING DIAGNOSIS AND PHOTODYNAMIC THERAPY, AND PREPARATION METHOD THEREFOR 서울대학교산학협력단 2020-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061083-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR TSPO, FABP7, SLC46A1 HTR7 1032/4885POLB 4372/4885APEX1 4345/4885
US-12491271-B2 Positron emission tomography radiotracer for diseases associated with translocator protein overexpression, translocator protein-targeting ligand for fluorescence imaging-guided surgery and photodynamic therapy, and production methods therefor TSPO, FABP7, SLC46A1 HTR7 772/4885POLB 4484/4885APEX1 3982/4885
US-20240156997-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR TSPO, FABP7, SLC46A1 HTR7 772/4885POLB 4484/4885APEX1 3982/4885
US-20200345870-A1 POSITRON EMISSION TOMOGRAPHY RADIOTRACER FOR DISEASES ASSOCIATED WITH TRANSLOCATOR PROTEIN OVEREXPRESSION, TRANSLOCATOR PROTEIN-TARGETING LIGAND FOR FLUORESCENCE IMAGING-GUIDED SURGERY AND PHOTODYNAMIC THERAPY, AND PRODUCTION METHODS THEREFOR TSPO, TMEM14C, FABP7 HTR7 1191/4885POLB 4522/4885APEX1 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.