Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.56 |
| ▸ | ADK | P55263 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862688 | 1.00 | HIF1A (0.56) | HIF1ASLC29A1ADKLMNAALDH1A1 | |
| SCHEMBL7990561 | 0.88 | LMNA (0.68) | HIF1ASLC29A1ADKLMNAALDH1A1 | |
| SCHEMBL20925387 | 0.83 | ADORA1 (0.56) | HIF1ASLC29A1ADKLMNAALDH1A1 | |
| SCHEMBL22349483 | 0.82 | HIF1A (0.64) | HIF1ASLC29A1 | |
| SCHEMBL2284604 | 0.81 | HIF1A (0.67) | HIF1ASLC29A1 | |
| SCHEMBL2284612 | 0.81 | HIF1A (0.67) | HIF1ASLC29A1 | |
| SCHEMBL18486201 | 0.81 | SLC29A1 (0.57) | HIF1ASLC29A1ADKLMNAALDH1A1 | |
| SCHEMBL23982373 | 0.80 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL6267085 | 0.80 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL548569 | 0.80 | HIF1A (0.71) | HIF1ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10744209-B2 | Biodegradable polymeric nanoparticle conjugates and use thereof | NEW YORK UNIVERSITY (US) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10744209-B2 | Biodegradable polymeric nanoparticle conjugates and use thereof | CD47, SLC46A1, ABCB1 | HIF1A 238/4885SLC29A1 388/4885ADK 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.