Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820129 | 0.77 | TDP1 (0.53) | TDP1KDM4EL3MBTL1MAPK1KMT2A | |
| SCHEMBL18573740 | 0.76 | RAB9A (0.48) | TDP1KDM4EL3MBTL1MAPK1KMT2A | |
| SCHEMBL22349634 | 0.75 | LMNA (0.51) | TDP1KDM4EL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL19820140 | 0.73 | TDP1 (0.51) | TDP1KDM4EL3MBTL1MAPK1KMT2A | |
| SCHEMBL20793272 | 0.73 | RAB9A (0.48) | TDP1KDM4EL3MBTL1MAPK1KMT2A | |
| SCHEMBL18430848 | 0.73 | TDP1 (0.47) | TDP1L3MBTL1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL21572853 | 0.72 | TDP1 (0.58) | TDP1KDM4EL3MBTL1MAPK1KMT2A | |
| SCHEMBL4812204 | 0.72 | ALDH1A1 (0.54) | DHODHTDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL20757052 | 0.72 | TDP1 (0.50) | TDP1KDM4EL3MBTL1MAPK1KMT2A | |
| SCHEMBL28216134 | 0.72 | ALDH1A1 (0.54) | DHODHTDP1L3MBTL1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10749118-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10749118-B2 | Heterocyclic compound and organic light-emitting device including the same | CYP1A1, CRY1, CYP1B1 | DHODH 1047/4885TDP1 3358/4885KDM4E 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.