Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 4/20 | 0.44 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22352154 | 0.85 | BCHE (0.53) | ADORA1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL13488853 | 0.85 | BCHE (0.53) | ADORA1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL12149869 | 0.85 | BCHE (0.53) | ADORA1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL19778463 | 0.82 | ADK (0.48) | MARS1ADKADORA1ADORA2API4KA | |
| SCHEMBL8923800 | 0.82 | ADORA2A (0.56) | ADORA1ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL20782297 | 0.80 | TRPM2 (0.49) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL22887211 | 0.80 | P2RX3 (0.55) | TRPM2SRCP2RY2P2RY1SMN1; SMN2 | |
| SCHEMBL18840499 | 0.79 | P2RX3 (0.57) | TRPM2SRCP2RY2P2RY1SMN1; SMN2 | |
| SCHEMBL20782392 | 0.78 | TDP1 (0.53) | MARS1ADORA1ADORA2ADNPH1PDE4D | |
| SCHEMBL24220759 | 0.78 | ADORA1 (0.56) | ADORA1ADORA2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |