Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280356 | 0.85 | KDM1A (0.41) | CA1CA2CA12CA9PGR | |
| SCHEMBL19577030 | 0.83 | P2RX4 (0.46) | — | |
| SCHEMBL19551440 | 0.80 | CA12 (0.52) | CA1CA2CA12CA9 | |
| SCHEMBL29782427 | 0.79 | CA12 (0.35) | CA1CA2CA12CA9SCN9A | |
| SCHEMBL19551567 | 0.79 | CA12 (0.35) | CA1CA2CA12CA9SCN9A | |
| SCHEMBL19551603 | 0.79 | P2RX4 (0.53) | — | |
| SCHEMBL19551428 | 0.78 | P2RX4 (0.47) | ENPP1 | |
| SCHEMBL28279131 | 0.77 | NLRP3 (0.46) | CA1CA2CA12CA9 | |
| SCHEMBL19551485 | 0.77 | LMNA (0.40) | CA1CA2CA12CA9 | |
| SCHEMBL28280449 | 0.77 | LMNA (0.43) | CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |