Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453506 | 0.89 | KDM4E (0.48) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28264084 | 0.82 | TDP1 (0.50) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28266659 | 0.82 | LMNA (0.50) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28270530 | 0.82 | MAPK13 (0.54) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28116018 | 0.82 | TDP1 (0.50) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28147084 | 0.81 | TAAR1 (0.53) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| Phenol SCHEMBL28258861 | 0.80 | RPS6KA3 (0.45) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28115678 | 0.79 | LTA4H (0.46) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28757943 | 0.78 | CNR1 (0.45) | RAB9AKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28036308 | 0.78 | KDM4E (0.54) | RAB9AKDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161835-B2 | Compounds and their use for reducing uric acid levels | ACQUIST LLC (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200339545-A1 | Compounds And Their Use For Reducing Uric Acid Levels | ACQUIST LLC (US) | 2020-10-29 | — | — | US | disclosed |
| US-10752613-B2 | Compounds and their use for reducing uric acid levels | ACQUIST LLC (US) | 2020-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339545-A1 | Compounds And Their Use For Reducing Uric Acid Levels | XDH, OAT, PON1 | RAB9A 2502/4885KDM4E 4498/4885NPC1 790/4885 |
| US-11161835-B2 | Compounds and their use for reducing uric acid levels | XDH, OAT, PON1 | RAB9A 2502/4885KDM4E 4498/4885NPC1 790/4885 |
| US-10752613-B2 | Compounds and their use for reducing uric acid levels | XDH, OAT, PON1 | RAB9A 2502/4885KDM4E 4498/4885NPC1 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.