Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22354570 | 0.85 | ALDH1A1 (0.41) | ALDH1A1USP2KDM4EALOX15SMN1; SMN2 | |
| SCHEMBL25587776 | 0.83 | ALDH1A1 (0.43) | ALDH1A1USP2KDM4EALOX15SMN1; SMN2 | |
| SCHEMBL23869628 | 0.81 | TLR2 (0.38) | ALDH1A1USP2KDM4EALOX15SMN1; SMN2 | |
| SCHEMBL18751382 | 0.77 | ALDH1A1 (0.41) | ALDH1A1USP2KDM4ESMN1; SMN2ABCB1 | |
| SCHEMBL15025393 | 0.74 | PDE4A (0.41) | ALDH1A1USP2KDM4EALOX15MEN1 | |
| SCHEMBL15025259 | 0.74 | TLR2 (0.36) | ALDH1A1USP2KDM4EALOX15SMN1; SMN2 | |
| SCHEMBL29321107 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNATLR2 | |
| SCHEMBL29321098 | 0.73 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNATLR2 | |
| SCHEMBL8014369 | 0.73 | ALDH1A1 (0.49) | ALDH1A1LMNATHRBMAPTTLR2 | |
| SCHEMBL8014365 | 0.73 | ALDH1A1 (0.49) | ALDH1A1LMNATHRBMAPTTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230131943-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | BURNET MICHEAL W (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230131943-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | BURNET MICHEAL W (DE) | 2023-04-27 | — | — | US | disclosed |
| WO-2021195126-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | BURNET MICHAEL W (DE) | 2021-09-30 | — | — | WO | disclosed |
| US-20200262857-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | SYNOVO GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131943-A1 | ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS | CTSA, GAA, SLC7A5 | ALDH1A1 3317/4885USP2 571/4885KDM4E 3394/4885 |
| US-20230159581-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | CTSA, ALOX15, ALOX5 | ALDH1A1 947/4885USP2 928/4885KDM4E 3648/4885 |
| US-20200262857-A1 | NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS | CTSA, ALOX15, ALOX5 | ALDH1A1 947/4885USP2 928/4885KDM4E 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.