Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 14/20 | 0.46 |
| ▸ | PTGES | O14684 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233918 | 0.88 | PSEN1 (0.51) | ALOX5PSEN1PTGESPPARG | |
| SCHEMBL13582375 | 0.83 | PTGER3 (0.44) | — | |
| SCHEMBL13582372 | 0.83 | PTGER3 (0.44) | — | |
| SCHEMBL2235542 | 0.83 | NR4A2 (0.41) | — | |
| SCHEMBL2235535 | 0.83 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL2231815 | 0.78 | PSEN1 (0.51) | ALOX5PSEN1PTGESPPARG | |
| SCHEMBL2235847 | 0.77 | ALOX5 (0.41) | ALOX5PSEN1PTGESPPARG | |
| SCHEMBL2231994 | 0.75 | PSEN1 (0.48) | ALOX5PSEN1PTGESPPARG | |
| SCHEMBL13582813 | 0.75 | MEN1 (0.43) | PPARG | |
| SCHEMBL13582816 | 0.75 | MEN1 (0.43) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |