Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 16/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 15/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.51 |
| ▸ | PTGES | O14684 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231994 | 0.91 | PSEN1 (0.48) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2233918 | 0.90 | PSEN1 (0.51) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2231811 | 0.82 | ACACB (0.39) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL13582482 | 0.82 | PTGER3 (0.41) | PPARG | |
| SCHEMBL13582479 | 0.82 | PTGER3 (0.41) | PPARG | |
| SCHEMBL2231809 | 0.82 | ACACB (0.38) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2233914 | 0.78 | ACACB (0.41) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2235546 | 0.78 | ALOX5 (0.46) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2231793 | 0.76 | PPARG (0.48) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2231990 | 0.74 | RAB9A (0.38) | PSEN1ALOX5PPARGPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |