Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22356641 | 0.77 | ADORA3 (0.46) | NPY5RTNIKIDO1RAB9ANPC1 | |
| SCHEMBL18704308 | 0.75 | KMT2A (0.49) | RXFP1TRPV1LMNAPOLBBRD9 | |
| SCHEMBL22356726 | 0.75 | FGFR4 (0.73) | NPY5RFGFR4LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL1502279 | 0.74 | IDO1 (0.45) | RXFP1TRPV1LMNAPOLBBRD9 | |
| SCHEMBL18535719 | 0.69 | BRD9 (0.50) | RXFP1TRPV1LMNAPOLBBRD9 | |
| SCHEMBL2880191 | 0.69 | LMNA (0.54) | RXFP1LMNAPOLBBRD9METAP1 | |
| SCHEMBL28444082 | 0.69 | CHRM3 (0.52) | LMNABRD9 | |
| SCHEMBL22356643 | 0.69 | NPY5R (0.41) | NPY5RTNIKKDRRETRAB9A | |
| SCHEMBL4414634 | 0.68 | LMNA (0.48) | RXFP1TRPV1LMNAPOLBBRD9 | |
| SCHEMBL2940952 | 0.67 | GAA (0.51) | RXFP1LMNAPOLBBRD9METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262827-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | BIOARDIS LLC (US) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262827-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | FGFR4, FGFR1, FGFR3 | RXFP1 627/4885NPY5R 1264/4885TNIK 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.