Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | FLT1 | P17948 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22356641 | 0.73 | ADORA3 (0.46) | NPY5RNPC1RAB9ATNIK | |
| SCHEMBL28378015 | 0.69 | ENPP2 (0.46) | ALDH1A1ENPP2KDRFLT1FLT3 | |
| SCHEMBL22356644 | 0.69 | RXFP1 (0.43) | NPY5RKDRNPC1RAB9ARET | |
| SCHEMBL28378012 | 0.67 | USP30 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL26068711 | 0.65 | ALDH1A1 (0.66) | L3MBTL1ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL5162705 | 0.63 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6687005 | 0.63 | ALDH1A1 (0.68) | L3MBTL1ALDH1A1MAPK1KMT2A | |
| SCHEMBL15888187 | 0.63 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPK1ENPP2PPARG | |
| SCHEMBL15647513 | 0.63 | MGLL (0.67) | L3MBTL1ALDH1A1MAPK1ENPP2NPC1 | |
| SCHEMBL27499661 | 0.62 | ALDH1A1 (0.92) | L3MBTL1ALDH1A1MAPK1ENPP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262827-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | BIOARDIS LLC (US) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262827-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | FGFR4, FGFR1, FGFR3 | NPY5R 1264/4885L3MBTL1 4857/4885ALDH1A1 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.