SCHEMBL22357191

SCHEMBL22357191

Cc1cc(C(=O)OC[C@H]2CO2)c(C)cc1C(=O)OCC1CO1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
DHFR P00374 1/20 0.45
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MGLL Q99685 3/20 0.41
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GLA P06280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1714542 1.00 ALDH1A1 (0.47) ALDH1A1DHFRTP53CYP3A4MGLL
SCHEMBL22357193 0.95 ALDH1A1 (0.46) ALDH1A1DHFRTP53CYP3A4MGLL
SCHEMBL27669935 0.94 ALDH1A1 (0.42) ALDH1A1DHFRTP53CYP3A4MGLL
SCHEMBL1646377 0.93 ALDH1A1 (0.47) ALDH1A1DHFRTP53CYP3A4MGLL
SCHEMBL157854 0.87 DHFR (0.48) ALDH1A1DHFRTP53CYP3A4MGLL
SCHEMBL1376714 0.85 DHFR (0.43) ALDH1A1DHFRMGLL
SCHEMBL2493818 0.83 DHFR (0.42) ALDH1A1DHFRMGLL
SCHEMBL1714954 0.83 ALDH1A1 (0.45) ALDH1A1DHFRTP53CYP3A4MGLL
SCHEMBL1715642 0.82 DHFR (0.43) ALDH1A1DHFRTP53MGLLMAPK1
SCHEMBL1714352 0.82 DHFR (0.45) ALDH1A1DHFRTP53CYP3A4MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020166580-A1 METHOD FOR PRODUCING POLYMER 日産化学株式会社 2020-08-20 WO disclosed