SCHEMBL2235751

SCHEMBL2235751

C=C[Si](C)(O)c1ccc([Si](C)(O)C=C)cc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.41
NR1H3 Q13133 2/20 0.41
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
HPGD P15428 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL464990 0.87 ESR1 (0.41) NR1H2NR1H3ESR1ESR2HDAC8
SCHEMBL10944501 0.71 NR1H2 (0.34) NR1H2NR1H3
SCHEMBL678612 0.71 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL5771954 0.71 NR1H2 (0.39) NR1H2NR1H3
SCHEMBL30423535 0.67 ALDH1A1 (0.52) NR1H2NR1H3HDAC8
SCHEMBL29214160 0.67 NFE2L2 (0.38) NR1H2NR1H3
SCHEMBL31231940 0.67 NR1H2 (0.55) NR1H2NR1H3
SCHEMBL15473032 0.67 ALDH1A1 (0.52) NR1H2NR1H3HDAC8
SCHEMBL29214103 0.67 NR1H2 (0.37) NR1H2NR1H3
SCHEMBL2558126 0.67 NR1H2 (0.55) NR1H2NR1H3ESR1ESR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2361284-B1 FLUORINATED BIS-(PHTHALOCYANYLALUMINOXY)SILYL PIGMENTS GLOBAL OLED TECHNOLOGY LLC (US) 2013-05-01 EP disclosed
EP-2361284-A2 FLUORINATED BIS-(PHTHALOCYANYLALUMINOXY)SILYL PIGMENTS Global OLED Technology LLC (US) 2011-08-31 EP disclosed
WO-2010053510-A2 FLUORINATED BIS-(PHTHALOCYANYLALUMINOXY)SILYL PIGMENTS GLOBAL OLED TECHNOLOGY LLC (US) 2010-05-14 WO disclosed
US-7628849-B1 Fluorinated bis-(phthalocyanylaluminoxy)silyl pigments EASTMAN KODAK COMPANY (US) 2009-12-08 US disclosed