SCHEMBL22357635

SCHEMBL22357635

c1ccc(-c2ccc3nc4n(-c5ccccc5)c5ccc(-c6ccc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)cc6)cc5n4c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 2/20 0.39
AVPR1A P37288 1/20 0.39
ADORA1 P30542 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
HCAR1 Q9BXC0 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
MAPK14 Q16539 1/20 0.34
BACE1 P56817 1/20 0.33
HSP90AA1 P07900 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22357659 1.00 ADORA2B (0.39) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357653 1.00 ADORA2B (0.39) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357580 0.97 ESR1 (0.38) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357652 0.95 ADORA2B (0.42) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22662003 0.95 ADORA2B (0.42) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL25106483 0.94 MEN1 (0.41) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357615 0.94 MEN1 (0.41) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357568 0.94 MEN1 (0.41) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357561 0.94 MEN1 (0.41) ADORA2BAVPR1AADORA1ESR1ESR2
SCHEMBL22357663 0.94 MEN1 (0.41) ADORA2BAVPR1AADORA1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309390-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-09-28 US disclosed
US-20230309390-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-09-28 US disclosed
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230069900-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-03-09 US disclosed
US-11552258-B2 Organic light-emitting device comprising emission layer satisfying specific singlet excitation energy level conditions SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-10 US disclosed
US-20220149287-A1 ORGANIC LIGHT-EMITTING DEVICE Research & Business Foundation Sungkyunkwan University (KR) 2022-05-12 US disclosed
US-20210284906-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-09-16 US disclosed
US-20200321537-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-08 US disclosed
US-20200266360-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200266360-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CCNE2, CRY1, CCNE1 ADORA2B 4437/4885AVPR1A 1551/4885ADORA1 3927/4885
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP2E1, AOX1 ADORA2B 4133/4885AVPR1A 2536/4885ADORA1 3418/4885
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 ADORA2B 3759/4885AVPR1A 2196/4885ADORA1 2450/4885
US-11552258-B2 Organic light-emitting device comprising emission layer satisfying specific singlet excitation energy level conditions EML4, NES, TBL2 ADORA2B 3099/4885AVPR1A 4467/4885ADORA1 3574/4885
US-20230309390-A1 ORGANIC LIGHT-EMITTING DEVICE L1CAM, EML4, OR10J3 ADORA2B 3724/4885AVPR1A 4420/4885ADORA1 3917/4885
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 ADORA2B 3961/4885AVPR1A 2412/4885ADORA1 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.