Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22357734 | 0.96 | PDE2A (0.42) | PDE2APDE10ALMNAHTTSMN1; SMN2 | |
| SCHEMBL18939806 | 0.89 | ACHE (0.48) | LMNASMN1; SMN2ALDH1A1ACHEGAA | |
| SCHEMBL18938467 | 0.89 | LMNA (0.44) | PDE2APDE10ALMNAHTTSMN1; SMN2 | |
| SCHEMBL18938480 | 0.87 | LMNA (0.43) | PDE2APDE10ALMNAHTTSMN1; SMN2 | |
| SCHEMBL22357674 | 0.85 | SRC (0.42) | PDE2ALMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL18940048 | 0.79 | LMNA (0.38) | PDE2APDE10ALMNAHTTSMN1; SMN2 | |
| SCHEMBL18938806 | 0.79 | NPC1 (0.50) | LMNASMN1; SMN2MAPK1ALDH1A1ACHE | |
| SCHEMBL22357795 | 0.79 | ACHE (0.39) | SMN1; SMN2ACHEGAA | |
| SCHEMBL18920600 | 0.79 | PTGES (0.43) | PDE2APDE10ALMNAHTTSMN1; SMN2 | |
| SCHEMBL18920586 | 0.79 | SMN1; SMN2 (0.41) | PDE2APDE10ALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262799-A1 | PROCESS FOR PREPARING FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS | UNIVERSITE DE BOURGOGNE (FR) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262799-A1 | PROCESS FOR PREPARING FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS | CYP4Z1, CYP4F12, CYP3A5 | PDE2A 3950/4885PDE10A 4218/4885LMNA 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.