SCHEMBL22360333

SCHEMBL22360333

CNCc1ccccc1-c1cccc(-c2ccccc2)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 4/20 0.46
CD274 Q9NZQ7 7/20 0.44
SCN8A Q9UQD0 1/20 0.44
LTA4H P09960 1/20 0.43
PDCD1 Q15116 3/20 0.40
NR1H4 Q96RI1 1/20 0.40
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
IFNAR1 P17181 1/20 0.38
FABP7 O15540 1/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
DPP4 P27487 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22590593 0.82 CD274 (0.43) CD274SCN8APDCD1NR1H4KMT2A
SCHEMBL417693 0.81 LTA4H (0.55) HTR7CD274SCN8ALTA4HPDCD1
SCHEMBL13385087 0.79 PDE4B (0.48) CD274PDCD1NR1H4KDM4EALDH1A1
SCHEMBL31613044 0.76 HTR1A (0.43) HTR7CD274SCN8ALTA4HPDCD1
SCHEMBL8281062 0.75 HTR7 (0.52) HTR7CD274MEN1POLBKMT2A
SCHEMBL11293298 0.75 PDCD1 (0.59) CD274SCN8APDCD1NR1H4KMT2A
SCHEMBL22910533 0.75 CD274 (0.65) CD274SCN8ALTA4HPDCD1DPP4
SCHEMBL25805583 0.75 CD274 (0.50) HTR7CD274SCN8ALTA4HPDCD1
SCHEMBL20957481 0.73 PDCD1 (0.44) HTR7CD274SCN8APDCD1NR1H4
SCHEMBL28841110 0.73 PDCD1 (0.44) HTR7CD274SCN8APDCD1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11077433-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2021-08-03 US disclosed
US-20200261898-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261898-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 HTR7 1624/4885CD274 4075/4885SCN8A 2851/4885
US-11077433-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 HTR7 1624/4885CD274 4075/4885SCN8A 2851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.