Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360409 | 0.88 | TDP1 (0.51) | LMNAATMMAPTTSHRL3MBTL1 | |
| SCHEMBL22360410 | 0.85 | MAPT (0.46) | MAPTTSHRL3MBTL1NPC1RAB9A | |
| SCHEMBL22360377 | 0.85 | RAB9A (0.55) | LMNAMAPTTSHRL3MBTL1NPC1 | |
| SCHEMBL22360404 | 0.85 | TP53 (0.50) | LMNAMAPTTSHRL3MBTL1NPC1 | |
| SCHEMBL22360412 | 0.80 | MAPT (0.42) | LMNASIRT2MAPTTSHRNPY1R | |
| SCHEMBL22360413 | 0.79 | HDAC1 (0.43) | LMNASIRT2MAPTTSHRNPY1R | |
| SCHEMBL22360403 | 0.79 | SMN1; SMN2 (0.55) | LMNAMAPTTSHRL3MBTL1NPC1 | |
| SCHEMBL22360411 | 0.78 | TSHR (0.39) | LMNASIRT2MAPTTSHRNPY1R | |
| SCHEMBL22360408 | 0.76 | NPC1 (0.46) | ATMMAPTTSHRL3MBTL1NPC1 | |
| SCHEMBL8900040 | 0.75 | LMNA (0.66) | LMNAATMSIRT2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |