Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360409 | 0.87 | TDP1 (0.51) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360388 | 0.86 | ACLY (0.42) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360403 | 0.86 | SMN1; SMN2 (0.55) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360406 | 0.85 | LMNA (0.52) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360404 | 0.84 | TP53 (0.50) | RAB9ANPC1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL22360385 | 0.83 | SMN1; SMN2 (0.45) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360386 | 0.83 | CASP3 (0.53) | RAB9ANPC1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL22360410 | 0.82 | MAPT (0.46) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360411 | 0.82 | TSHR (0.39) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL22360408 | 0.82 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |