Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | EPHB3 | P54753 | 4/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842161 | 0.85 | DRD4 (0.43) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL6608758 | 0.84 | DRD4 (0.42) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL3793299 | 0.82 | DRD4 (0.41) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL6748363 | 0.82 | DRD4 (0.41) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL23075880 | 0.82 | DRD4 (0.41) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| Hydrochloric Acid SCHEMBL3795000 | 0.81 | DRD4 (0.40) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| Hydrochloric Acid SCHEMBL3703425 | 0.81 | DRD4 (0.40) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL22932522 | 0.79 | DRD4 (0.39) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL19115073 | 0.79 | DRD3 (0.42) | DRD4DRD3EPHB3DYRK1AMAP4K4 | |
| SCHEMBL1290770 | 0.79 | DRD4 (0.39) | DRD4DRD3EPHB3DYRK1AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20200261455-A1 | INHIBITORS OF MUTANT FAMILY TYROSINE-KINASES | SPECTRUM PHARMACEUTICALS, INC. | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200261455-A1 | INHIBITORS OF MUTANT FAMILY TYROSINE-KINASES | ERBB2, EGFR, ERBB3 | DRD4 4813/4885DRD3 4622/4885EPHB3 383/4885 |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | DRD4 1861/4885DRD3 1018/4885EPHB3 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.