Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729693 | 0.81 | THRB (0.37) | MAPTTHRBGAAPOLBKDM4E | |
| SCHEMBL27318856 | 0.80 | NPC1 (0.42) | MAPTTHRBGAAPOLBSDCBP | |
| SCHEMBL24294314 | 0.79 | THRB (0.43) | MAPTTHRBGAAPOLBKDM4E | |
| SCHEMBL24294534 | 0.79 | THRB (0.43) | MAPTTHRBGAAPOLBKDM4E | |
| SCHEMBL24421373 | 0.79 | SDCBP (0.42) | MAPTTHRBGAAPOLBSDCBP | |
| SCHEMBL27121640 | 0.77 | MAPT (0.34) | ITGB3ITGA2BMAPTTHRBGAA | |
| SCHEMBL27115950 | 0.77 | THRB (0.35) | MAPTTHRBGAAPOLBSDCBP | |
| SCHEMBL21621851 | 0.76 | THRB (0.41) | MAPTTHRBGAAPOLBSDCBP | |
| SCHEMBL27124438 | 0.76 | KDM4E (0.38) | ITGB3ITGA2BTHRBGAAPOLB | |
| SCHEMBL23482963 | 0.75 | MAPT (0.39) | MAPTTHRBGAAPOLBSDCBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168172-A1 | CONJUGATE COMPOUNDS FOR THE DEGRADATION OF RAF | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-08-20 | — | — | WO | disclosed |