Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24294314 | 0.85 | THRB (0.43) | THRBMEN1KMT2ALMNAALOX15 | |
| SCHEMBL24294534 | 0.85 | THRB (0.43) | THRBMEN1KMT2ALMNAALOX15 | |
| SCHEMBL27318856 | 0.83 | NPC1 (0.42) | THRBMEN1KMT2ALMNAALOX15 | |
| SCHEMBL24421373 | 0.83 | SDCBP (0.42) | THRBMEN1KMT2ALMNAALOX15 | |
| SCHEMBL22360814 | 0.81 | ITGB3 (0.40) | THRBALOX15GAAKDM4EPOLB | |
| SCHEMBL25571489 | 0.80 | MAPT (0.36) | THRBLMNAALOX15GAAKDM4E | |
| SCHEMBL23128864 | 0.80 | MAPT (0.36) | THRBLMNAALOX15GAAKDM4E | |
| SCHEMBL25032020 | 0.79 | ALOX15 (0.40) | THRBMEN1KMT2ALMNAALOX15 | |
| SCHEMBL24779146 | 0.79 | SDCBP (0.36) | THRBALOX15GAAKDM4EPOLB | |
| SCHEMBL23482963 | 0.79 | MAPT (0.39) | THRBMEN1KMT2ALMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |