Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.69 |
| ▸ | CA9 | Q16790 | 9/20 | 0.69 |
| ▸ | CA1 | P00915 | 7/20 | 0.69 |
| ▸ | CA12 | O43570 | 5/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177204 | 0.83 | TSHR (0.57) | CA2CA1ALDH1A1LMNAGAA | |
| SCHEMBL3519559 | 0.83 | CA2 (1.00) | CA2CA9CA1CA12CA4 | |
| SCHEMBL2237810 | 0.81 | STS (0.57) | CA2CA9CA1CA12STS | |
| SCHEMBL2235949 | 0.80 | CA2 (0.66) | CA2CA9CA1CA12STS | |
| SCHEMBL2239304 | 0.80 | CA2 (0.66) | CA2CA9CA1CA12STS | |
| SCHEMBL2237446 | 0.80 | CA2 (0.57) | CA2CA9CA1CA12STS | |
| SCHEMBL2237247 | 0.80 | CA2 (0.65) | CA2CA9CA1CA12STS | |
| SCHEMBL2236615 | 0.80 | CA2 (0.66) | CA2CA9CA1CA12STS | |
| SCHEMBL4667729 | 0.79 | CA2 (0.89) | CA2CA9CA1CA12CA4 | |
| SCHEMBL11291473 | 0.77 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
| EP-2533775-A1 | CARBONIC ANHYDRASE INHIBITORS | Universita' Degli Studi di Firenze (IT) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098610-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITA DEGLI STUDI DI FIRENZE (IT) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | CA2 2/4885CA9 1/4885CA1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.