Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235280 | 0.86 | MGLL (0.41) | MGLLADORA3ADORA1ALDH1A1POLB | |
| SCHEMBL11621784 | 0.86 | KMT2A (0.36) | MGLLADORA3ADORA1ALDH1A1MEN1 | |
| SCHEMBL11560644 | 0.86 | MGLL (0.41) | MGLLADORA3ADORA1ALDH1A1POLB | |
| SCHEMBL11557383 | 0.84 | ALDH1A1 (0.41) | MGLLADORA3ADORA1ALDH1A1POLB | |
| SCHEMBL11623489 | 0.82 | MGLL (0.38) | MGLL | |
| SCHEMBL2237065 | 0.82 | GRM2 (0.38) | MGLLADORA3ALDH1A1POLBMEN1 | |
| SCHEMBL11620783 | 0.78 | MAOA (0.41) | MAPT | |
| SCHEMBL11620916 | 0.77 | RAD51 (0.36) | MEN1KMT2AADRB1DRD2DRD3 | |
| SCHEMBL11620138 | 0.73 | P2RX7 (0.35) | MGLLALDH1A1ATMMEN1KMT2A | |
| SCHEMBL11121067 | 0.72 | USP2 (0.46) | ALDH1A1POLBMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150142-A | Derivatives of alkoxy-5-phenyl-3 oxadiazoline-1,3,4 one-2, their preparation and insecticidal and acaricidal compositions which contain them | PHILAGRO S.A. (FR) | 1979-04-17 | — | — | US | claimed |
| JP-57154108-A | — | — | None | — | — | JP | disclosed |
| US-8299264-B2 | Method for producing oxadiazolinone compound and intermediate thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20110207936-A1 | METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2357167-A1 | METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2011-08-17 | — | — | EP | disclosed |
| JP-S57154108-A | INSECTICIDE | MITSUBISHI CHEM IND LTD | 1982-09-22 | — | — | JP | disclosed |
| US-4150142-A | Derivatives of alkoxy-5-phenyl-3 oxadiazoline-1,3,4 one-2, their preparation and insecticidal and acaricidal compositions which contain them | PHILAGRO S.A. (FR) | 1979-04-17 | — | — | US | disclosed |
| US-4076824-A | Anthelmintic oxadiazolinone derivatives | RHONE-POULENC INDUSTRIES (FR) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207936-A1 | METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF | AHR, CYP1B1, AR | MGLL 4777/4885ADORA3 460/4885ADORA1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.