Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037741 | 0.76 | HPGD (0.54) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL9863137 | 0.75 | PPARA (0.67) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL29577774 | 0.75 | TP53 (0.62) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL655678 | 0.75 | TP53 (0.62) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL18439119 | 0.75 | TDO2 (0.56) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL7035256 | 0.74 | PPARA (0.50) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL11828515 | 0.73 | PPARA (0.63) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL16180353 | 0.72 | F9 (0.54) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL7028743 | 0.72 | PPARA (0.60) | F9F10PPARAPPARGKDM4E | |
| SCHEMBL6494581 | 0.72 | GAA (0.66) | PPARAPPARGKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759799-B2 | Indazole containing macrocycles and therapeutic uses thereof | SAMUMED, LLC (US) | 2020-09-01 | — | — | US | disclosed |
| US-10759799-B2 | Indazole containing macrocycles and therapeutic uses thereof | SAMUMED, LLC (US) | 2020-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759799-B2 | Indazole containing macrocycles and therapeutic uses thereof | WNT1, WNT3, WNT3A | F9 3910/4885F10 3722/4885PPARA 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.