SCHEMBL29700186

SCHEMBL29700186

CCN[C@@H](Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM6B O15054 1/20 0.57
▸ ALOX15 P16050 4/20 0.55
▸ KDM4E B2RXH2 4/20 0.55
▸ HIF1A Q16665 4/20 0.55
▸ HSD17B10 Q99714 4/20 0.55
▸ RECQL P46063 3/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ LCK P06239 2/20 0.55
▸ USP2 O75604 2/20 0.55
▸ ADORA3 P0DMS8 2/20 0.55
▸ HTR2A P28223 2/20 0.55
▸ PTGS2 P35354 2/20 0.55
▸ EGFR P00533 1/20 0.55
▸ FYN P06241 1/20 0.55
▸ PTGS1 P23219 1/20 0.55
▸ SLC7A5 Q01650 1/20 0.55
▸ MME P08473 1/20 0.53
▸ ACE P12821 1/20 0.53
▸ CA2 P00918 5/20 0.52
▸ CA1 P00915 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7433937 1.00 KDM6B (0.57) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL22364281 1.00 KDM6B (0.57) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL29759443 0.88 KDM6B (0.54) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL22364280 0.88 KDM6B (0.54) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL29926699 0.85 KDM6B (0.51) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL5207224 0.85 FOLH1 (0.46) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL31028433 0.85 KDM6B (0.51) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL25489225 0.85 MME (0.57) KDM6BALOX15KDM4EHIF1AHSD17B10
Hydrochloric Acid SCHEMBL10782448 0.84 KDM6B (0.61) KDM6BALOX15KDM4EHIF1AHSD17B10
SCHEMBL6340344 0.84 KDM6B (0.57) KDM6BALOX15KDM4EHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139250-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER BY TARGETING ONCOGENIC TRANSFER RNAS THE CHILDRENS MEDICAL CENTER CORP (US) 2026-05-21 — — US disclosed
US-20260091144-A1 BIO-ACTIVATED REPORTERS TO VISUALIZE, IN REAL TIME, SPECIFIC GENE THERAPY PRODUCTS UNIV NORTHWESTERN (US) 2026-04-02 — — US disclosed
US-12508328-B2 Bio-activated reporters to visualize, in real time, specific gene therapy products NORTHWESTERN UNIVERSITY (US) 2025-12-30 — — US disclosed
EP-4551702-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER BY TARGETING ONCOGENIC TRANSFER RNAS The Children's Medical Center Corporation (US) 2025-05-14 — — EP disclosed
US-11878057-B2 Immunomodulatory lipopolysaccharide compositions TRUSTEES OF BOSTON UNIVERSITY (US) 2024-01-23 — — US disclosed
WO-2024011118-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER BY TARGETING ONCOGENIC TRANSFER RNAS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-01-11 — — WO disclosed
EP-3541368-B1 IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF US HEALTH (US) 2023-07-12 — — EP disclosed
US-11382990-B2 Imageable polymers, methods of making and methods of use thereof THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) 2022-07-12 — — US disclosed
WO-2022125956-A1 IMMUNOMODULATORY LIPOPOLYSACCHARIDE COMPOSITIONS TRUSTEES OF BOSTON UNIVERSITY (US) 2022-06-16 — — WO disclosed
US-20220184206-A1 IMMUNOMODULATORY LIPOPOLYSACCHARIDE COMPOSITIONS TRUSTEES OF BOSTON UNIVERSITY (US) 2022-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382990-B2 Imageable polymers, methods of making and methods of use thereof PUF60, PBRM1, PCBP1 KDM6B 591/4885ALOX15 4457/4885KDM4E 1954/4885
US-20260139250-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER BY TARGETING ONCOGENIC TRANSFER RNAS TRDMT1, METTL16, TRMT1 KDM6B 1252/4885ALOX15 4577/4885KDM4E 821/4885
US-12508328-B2 Bio-activated reporters to visualize, in real time, specific gene therapy products GAA, GUSB, GBA3 KDM6B 1667/4885ALOX15 4528/4885KDM4E 4136/4885
US-20260091144-A1 BIO-ACTIVATED REPORTERS TO VISUALIZE, IN REAL TIME, SPECIFIC GENE THERAPY PRODUCTS GAA, GUSB, GBA3 KDM6B 1230/4885ALOX15 4597/4885KDM4E 3577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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