Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365070 | 0.80 | CHKA (0.55) | BACE1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15100943 | 0.77 | MGLL (0.62) | CYP2D6 | |
| SCHEMBL15094129 | 0.77 | MAPT (0.41) | BACE1SMN1; SMN2ALDH1A1HTR1ADRD2 | |
| SCHEMBL21802522 | 0.76 | BACE1 (0.54) | BACE1ATMMEN1KMT2AKDM4E | |
| SCHEMBL22273300 | 0.76 | MGLL (0.52) | KDM4EALDH1A1 | |
| SCHEMBL15266145 | 0.73 | BACE1 (0.47) | BACE1ATMMEN1KMT2AKDM4E | |
| SCHEMBL15094009 | 0.73 | MKNK2 (0.46) | SMN1; SMN2ALDH1A1LMNACYP3A4 | |
| SCHEMBL15094259 | 0.72 | PLA2G7 (0.64) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15094254 | 0.71 | RAB9A (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15093972 | 0.71 | DRD2 (0.45) | MEN1KMT2ASMN1; SMN2ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800565-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2014-11-12 | — | — | EP | claimed |
| WO-2013103973-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | ABIDE THERAPEUTICS (US) | 2013-07-11 | — | — | WO | claimed |